Breast cancer prevention infographic9/10/2023 Understanding more about the chemical and genetic makeup of your cancer may help doctors choose the most effective treatment for your specific cancer. Basal-like breast cancers are likely to benefit from chemotherapy. This type, which is also called triple-negative breast cancer, includes tumors that are ER negative, PR negative and HER2 negative. HER2 breast cancers are likely to benefit from chemotherapy and treatment targeted to HER2. This type includes tumors that are ER negative and PR negative, but HER2 positive. Luminal B breast cancers are likely to benefit from chemotherapy and may benefit from hormone therapy and treatment targeted to HER2. This type includes tumors that are ER positive, PR negative and HER2 positive. Luminal A breast cancers are likely to benefit from hormone therapy and may also benefit from chemotherapy. ![]() This group includes tumors that are ER positive and PR positive, but negative for HER2. These groups help guide decisions about which treatments are best. Ask your doctor whether this type of test might be helpful in your case.ĭoctors are increasingly using genetic information about breast cancer cells to categorize breast cancers. Tests that analyze the genetic makeup of breast cancers are available but aren't recommended in all situations. Breast Cancer UK estimates that around 30 of breast cancer cases in the UK can be prevented by making lifestyle changes This is equivalent to around 17,000 breast cancer cases each year For more information about breast cancer prevention see our Prevention Hub. That way, women with relatively low-risk breast cancers may avoid aggressive treatments. Doctors hope this information can be used to predict which cancers will spread and which may need aggressive treatments. Researchers are studying ways to interpret the genetic makeup of tumor cells. Targeted therapy drugs are available to shut down the HER2 protein, thus slowing the growth and killing these cancer cells. Cancer cells that have too many copies of the HER2 gene (HER2-positive cancers) produce too much of the growth-promoting protein called HER2. Get informed and check out the #ILCancerPlan for strategies (include the Screening and Early Detection infographic).A sample of your tumor tissue from a biopsy procedure may be tested in a laboratory to look for:
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